Lipoprotein Receptor Assays
The amount of cholesterol in the blood is mediated by the presence of certain cell-surface receptors which bind lipoproteins and engulf them by endocytosis. We have developed two new ELISA kits to measure lipoprotein receptors.
The physiological role of the LDL Receptor (LDLR) is to transport low-density lipoprotein particles into cells and is the primary pathway for removal of cholesterol from the circulation. Our Human LDLR Receptor ELISA Kit quantifies human LDLR in plasma, serum, or tissue homogenates or cell lysates.
OxLDL receptor LOX-1
The OxLDL receptor LOX-1 specifically binds the oxidized form of LDL. LOX-1 can be cleaved and released as a soluble form and is a prognostic biomarker of early acute coronary syndromes, stroke, and coronary heart disease. Our Human LOX-1 ELISA Kit was developed for the quantitation and detection of human LOX-1 in plasma, serum, or cell culture supernatants.
NGAL is a novel biomarker for diagnosing acute kidney injury (AKI). Under normal conditions NGAL levels are low in urine and plasma but rise sharply from basal levels in response to kidney injury to reach diagnostic levels within a very short time - as much as 24 hours or more before any significant rise in serum creatinine.